Figure 3.

Heart- and neural crest derivatives-expressed protein 2 (HAND2) expression is unaltered in human endometrial biopsies exposed to ulipristal acetate contraceptive vaginal ring (UPA-CVR). The percentages of the immunostaining positive cells for HAND2 were analyzed by ImageJ software. The values represent mean ± SEM of 12 independent samples (N = 5 for UPA-CVR releasing 1.5 mg and N = 7 for UPA-CVR releasing 2.5 mg UPA daily) with a total of N = 48 clinical samples. No obvious dose–response effects were noted between the 2 doses.