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. 2019 Jan 22;17:13. doi: 10.1186/s12958-019-0457-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Gestational HFD and its consequence on the estrous cycling activity after vaginal opening. a and b are representative animals for each group and day 0 corresponds to the first day after rats presented vaginal opening. Rats were observed for 15 days. c and d showed the percentage of the regularity and the age of puberty onset respectively (n = 12–15). *P < 0.05 HFD vs NCD, ***P < 0.001 HFD vs NCD