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. 2019 Jan 22;20:47. doi: 10.1186/s12859-018-2593-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Visualization of the methylation levels in chromosome scale. a The methyl-cytosine density in human chromosome 10. The dots represent the methylation levels in sliding windows of 100Kb with a step of 50Kb. The red dots refer to the methylation levels in the plus strand, and the blue dots refer to the methylation levels in the minus strand. b An example about the distributions of the DNA methylation levels and differentially-methylated regions (DMRs) between H9 and IMR90 cell lines in human chromosome 10. c The density of genes, transposon elements (TEs) and the level of DNA methylation in the whole rice genome. Panel A is the results generated from Batmeth2. Panel B is the visualization results from UCSC browser, with the BED files from Batmeth2