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. 2019 Jan 16;9:811. doi: 10.3389/fendo.2018.00811

Table 6.

Odds ratios (ORs) of the associations of four polymorphisms in the CD14 gene with GD before and after adjusting for confounders (age and gender).

Comparison models Unadjusted estimates Adjusted estimates
OR(95%CI) P-values OR (95%CI) P-values
rs2915863
Allele model 1.21 (1.04–1.41) 0.013 1.21 (1.04–1.40) 0.014
Dominant model 1.12 (0.89–1.41) 0.329 1.11 (0.88–1.39) 0.391
Recessive model 1.53 (1.18–1.98) 0.001 1.55 (1.20–2.00) 0.001
Homozygous model 1.23 (1.06–1.43) 0.006 1.23 (1.06–1.43) 0.006
Additive model 0.99 (0.77–1.26) 0.919 0.97 (0.76–1.24) 0.791
rs2569190
Allele model 1.21 (1.04–1.42) 0.012 1.21 (1.04–1.41) 0.014
Dominant model 1.22 (0.98–1.52) 0.073 1.21 (0.97–1.51) 0.089
Recessive model 1.42 (1.07–1.89) 0.015 1.42 (1.07–1.90) 0.015
Homozygous model 1.24 (1.06–1.45) 0.008 1.23 (1.05–1.45) 0.009
Additive model 1.13 (0.90–1.43) 0.281 1.12 (0.89–1.42) 0.335
rs2569192
Allele model 1.08 (0.86–1.37) 0.495 1.08 (0.86–1.37) 0.501
Dominant model 1.11 (0.86–1.42) 0.417 1.11 (0.86–1.42) 0.424
Recessive model 0.80 (0.25–2.55) 0.700 0.80 (0.25–2.57) 0.709
rs2563298
Allele model 1.07 (0.85–1.36) 0.546 1.07 (0.85–1.36) 0.557
Dominant model 1.08 (0.85–1.39) 0.495 1.09 (0.85–1.40) 0.509
Recessive model 0.88 (0.27–2.89) 0.839 0.90 (0.27–2.93) 0.855

Allele model = G vs. C; Dominant model = (GG+GC) vs. CC; Recessive model = GG vs. (GC+CC); Homozygous model = GG vs. CC; Additive model = GC vs. CC. Bold represents a positive P value.