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. 2019 Jan 17;114:e180332. doi: 10.1590/0074-02760180332

Fig. 4: (A) Posterior probability densities and root-to-tip analysis based on maximum likelihood tree (Supplementary data II (793.9KB, pdf) ) demonstrated a good temporal correlation (R2 = 0749), indicating that evolutionary clock models were appropriate for inferring the evolutionary origins of the West Nile virus (WNV) samples. It was used, with a relaxed uncorrelated log-normal molecular clock and a Bayesian skyline tree model. (B) Log marginal likelihood estimates, using distinct molecular clock and coalescent model combinations for temporal reconstruction using entire WNV open reading frames (ORFs) by path sampling model selection (PS) and stepping-stone model selection (SS) methods. The best-fitting model is highlighted in boldface. Coalescent models used were the parametric Constant models and the non-parametric was the Skygrid and Skyline models. The molecular clock models used were the strict molecular clock (Strict) and the uncorrelated relaxed lognormal molecular clock (UCLN). (C) Maximum clade credibility (MCC) tree of WNV genomes constructed using BEAST version 1.10.1 software. Colors of branches indicate geographic locations per the color key. Branch lengths correspond to lengths of time.

Fig. 4: