Skip to main content
. Author manuscript; available in PMC: 2019 Jan 23.
Published in final edited form as: ACS Chem Biol. 2018 Aug 27;13(9):2708–2718. doi: 10.1021/acschembio.8b00646

Figure 7. MBNL transcript and protein levels increased with furamidine treatment in DM1 myotubes.

Figure 7.

a) RT-qPCR data showing MBNL1 (sold bars) and MBNL2 (patterned bars) expression levels and western blot data for b) MBNL1 and c) MBNL2 protein levels in DM1 patient-derived myotubes treated with furamidine. Furamidine treatment caused increased levels of both MBNL1 and MBNL2 transcripts (p<0.01 or better for all). Also, MBNL1 protein levels increased between 0.25 and 0.75 μM furamidine (p<0.05 or better), while MBNL2 protein levels increased between 0.1 and 2 μM furamidine (p<0.05 or better).