Figure 6.

Lin⁻ CD61⁺ CD34⁻ CD45^low cells are present in additional sAML patients and exhibit TPO hypersensitivity a) Biaxials showing CD61 and CD45 expression in Lin⁻ CD61⁺ CD34⁻ cells in 3 separate sAML patient samples analyzed by Mass cytometry. b) upper: Biaxials showing STAT3 and STAT5 basal phosphorylation in sAML Lin⁻ CD34⁺ CD38⁻ cells compared to Lin⁻ CD61⁺ CD34⁻ CD45^low cells from in each patient; lower: Biaxials showing STAT3 and STAT5 TPO-mediated phosphorylation in sAML Lin⁻ CD34⁺ CD38⁻ cells compared to Lin⁻ CD61⁺ CD34⁻ CD45^low cells in each patient