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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Biotechnol Adv. 2018 Oct 9;37(1):1–20. doi: 10.1016/j.biotechadv.2018.10.003

Table 1.

General chromosomal features of S. coelicolor A3(2) (accession No: AL645882), S. lividans TK24 (accession No: NZ_CP009124), S. albus J1074 (accession No: NC_020990), S. venezuelae ATCC 15439 (accession No: NZ_CP013129), and S. avermitilis MA-4680 (accession No: AP002021-AP005050, BA000030 and AP005645).

SN Component S. coelicolor
A3(2)
S. lividans
TK24
S. albus
J1074
S. venezuelae
ATCC15439
S.avermitilis
MA-4680
1 Total Size (bp) 8,667,507 8,345,283 6,841,649 9,054831 9,025,608
2 G+C content (%) 72.12 72.24 73.3 71.74 70.7
3 Average gene length (bp) 991 - 1011 - 1034
4 Ribosomal RNAs (16S-23S-5S)
5 Transfer RNAs 63 64 66 72 68
6 Protein coding sequences 7825 7360 5832 8080 7346
7 Coding Density (%) 88.9 - 86.8 - -
8 Terminal inverted repeats (TIRs) 21,653 bp 31,000 bp 30,000 bp 49 bp
9 Doubling time ~ 2.2 h (S. coelicolor M145) ~ 4.2 h (S. lividans TK21) - ~ 1 h -
10 Method of gene introduction Conjugation/PEG-mediated transformation Mostly PEG-mediated transformation Conjugation/PEG-mediated transformation PEG-mediated transformation Conjugation/PEG-mediated transformation
11 Restriction barriers Methyl-specific restriction No methyl-specific restriction Methyl-specific restriction Methyl-specific restriction Methyl-specific restriction

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