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. Author manuscript; available in PMC: 2019 Jan 23.
Published in final edited form as: Leukemia. 2018 Jul 27;32(9):2090–2092. doi: 10.1038/s41375-018-0217-7

Figure 1.

Figure 1.

2mFo-DFc (blue, contoured at 1.5σ) and mFo-DFc (green/red, 3.0σ/–3.0σ) electron densities for the original (a and c) and re-refined (b and d) structures for two representative regions, shown in wall-eye stereo views. The original and re-refined models are shown in yellow and cyan sticks, respectively. The red cross-hairs in a represent water molecules. Strong positive difference density corresponding to the missing nucleotide (a) or phosphodiester bond (c) is indicated by the green arrows.