Table 1.
Structurally characterized Rab:effector complexes.
| Rab: effector complex | stoichiometry | pdb id | KD | references |
|---|---|---|---|---|
| Rab3a: Rabphilin-3a/Exophilin1 | 1:1 | 1zbd | — | 44 |
| Rab4: Rabenosyn-5440–503 | 1:1 | 1z0k | 6.2 µM | 19 |
| Rab5a: EEA1 | 1:1 | 3mjh | 2.4 µM | 14 |
| Rab6: Rab6IP1 | 1:1 | 3cwz | — | 45 |
| Rab8a: OCRL1 | 1:1 | 3qbt | 0.9 µM | 15 |
| Rab11a: MyoVb | 1:1 | 4lx0 | 254 nM | 13 |
| Rab22: Rabenosyn-5728–784 | 1:1 | 1z0j | 9.7 µM | 19 |
| Rab27a: Slp2-a/Exophilin4 | 1:1 | 3bc1 | 13.4 nM | 46,47 |
| Rab27a: Slac2-a/Melanophilin | 1:1 | 2zet | 112 nM | 47,48 |
| Rab5a: Rababtin-5 | 2:2 | 1tu3 | — | 23 |
| Rab6: Gcc185 | 2:2 | 3bbp | 2.3 µM | 22 |
| Rab7: RILP | 2:2 | 1yhn | — | 24 |
| Rab11a: Fip2 | 2:2 | 2 gzh | 40 nM | 25,49 |
| Rab32: VARP/AnkRD27 | 2:2 | 4cym | 2.5 µM | 12 |
| Rab10:Mical-1 | 2:1 | 5lpn | — | 18 |