Table 1.
Genetic aberrations identified in three samples.
| Gene | Gene.ID | AA Change | Chr. start | Chr. end | Plasma | MPE | Ascites | COSMIC |
|---|---|---|---|---|---|---|---|---|
| ATM | ATM:NM_000051.3:exon48 | p.E2351A (c.A7052C) | chr11:108198448 | chr11:108198448 | 8% | 5% | 24% | - |
| ATM | ATM:NM_000051.3:exon48 | p.NPAVIM2353delinsK | chr11:108198452 | chr11:108198466 | 8% | 5% | 24% | - |
| ATM | ATM:NM_000051.3:exon35 | p.D1758fs | chr11:108172469 | chr11:108172479 | 6% | 5% | 24% | - |
| ATM-BPIFB1 | gene fusion | 14% | 6% | 20% | - | |||
| MET | gene amplification | 2 copies | 1.8copies | 2.4copies | 3.27% | |||
| SMAD3 | SMAD3:NM_005902.3:exon8 | p.R368X (c.C1102T) | chr15:67479795 | chr15:67479795 | 22% | 9% | 67% | - |
| TEK | gene amplification | - | - | 2.5copies | 0.82% |