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. 2018 Aug 23;20(1):65–72. doi: 10.1080/15384047.2018.1504725

Figure 4.

Figure 4.

Detection of tumor cell apoptosis by TUNEL staining.

Abbreviations: TMZ, temozolomide; AAV2-VEGF-Trap, adeno-associated virus 2 mediated gene transfer of vascular endothelial growth factor Trap; BEV, bevacizumab.

(A) TUNEL staining in each group (magnification, ×200).

(B) The positive rate of TUNEL staining in each group.

P values: *: TMZ+AAV2-VEGF-Trap group and TMZ+BEV group vs. TMZ group, <0.05; TMZ+AAV2-VEGF-Trap group and TMZ+BEV group vs. AAV2-VEGF-Trap group, BEV group and control group, <0.01. And there was no difference between TMZ+AAV2-VEGF-Trap group and TMZ+BEV group (> 0.05), among AAV2-VEGF-Trap group, BEV group and the control group (> 0.05).