Table 2.

Changes in ADC values of tumor in each group at 7d, 14d and 21d.

Groups	ADC values of tumor (×10−3mm2/s)
	7d	14d	21d
TMZ+AAV2-VEGF-Trap	1.02 ± 0.11	1.35 ± 0.18**	1.46 ± 0.19**
TMZ+BEV	0.93 ± 0.19	1.31 ± 0.13**	1.38 ± 0.10**
TMZ	0.93 ± 0.14	1.02 ± 0.14*	1.16 ± 0.21*
AAV2-VEGF-Trap	1.06 ± 0.14	1.16 ± 0.12*	1.17 ± 0.13*
BEV	1.04 ± 0.18	1.15 ± 0.20*	1.19 ± 0.18*
Control	1.07 ± 0.14	0.85 ± 0.13	0.74 ± 0.13

Abbreviations: TMZ, temozolomide; AAV2-VEGF-Trap, adeno-associated virus 2 mediated gene transfer of vascular endothelial growth factor Trap; BEV, bevacizumab.

P values:

**: TMZ+AAV2-VEGF-Trap group and TMZ+BEV group vs. control group, ＜0.05;

*: TMZ group, AAV2-VEGF-Trap group and BEV group vs. control group, ＞0.05.