Table 2.
Number of dysregulated genes for 14 selected pathways, in each time point.
| 1 h |
2 h |
4 h |
6 h |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| PATHWAY | UP | DOWN | UP | DOWN | UP | DOWN | UP | DOWN | Average UP | Average DOWN |
| APOPTOSIS | 314 | 145 | 67 | 45 | 286 | 143 | 101 | 14 | 192 | 86,75 |
| OXIDATIVE STRESS | 159 | 79 | 158 | 114 | 149 | 78 | 227 | 44 | 173,25 | 78,75 |
| FATTY ACIDS METABOLISM | 255 | 108 | 436 | 326 | 226 | 139 | 692 | 119 | 402,25 | 173 |
| PHOTOTRANSDUCTION | 295 | 97 | 284 | 168 | 281 | 172 | 382 | 53 | 310,5 | 122,5 |
| SIGNAL TRANSDUCTION | 869 | 300 | 899 | 547 | 818 | 323 | 1291 | 157 | 969,25 | 331,75 |
| CYTOSKELETON AND TRAFFICKING | 930 | 339 | 899 | 626 | 834 | 406 | 1351 | 205 | 1003,5 | 394 |
| RNA PROCESSING | 122 | 69 | 120 | 95 | 103 | 76 | 185 | 33 | 132,5 | 68,25 |
| SPLICING | 75 | 40 | 82 | 56 | 71 | 46 | 140 | 13 | 92 | 38,75 |
| PROTEOSTASIS | 711 | 240 | 653 | 394 | 625 | 279 | 1048 | 127 | 759,25 | 260 |
| MITOCHONDRION | 250 | 146 | 263 | 221 | 225 | 166 | 400 | 106 | 284,5 | 159,75 |
| INFLAMMATION | 97 | 53 | 98 | 81 | 87 | 56 | 148 | 35 | 107,5 | 56,25 |
| NEURON | 277 | 85 | 269 | 178 | 248 | 108 | 390 | 45 | 296 | 104 |
| EPIGENETIC | 231 | 77 | 220 | 121 | 210 | 80 | 352 | 22 | 253,25 | 75 |
| CIRCADIAN RHYTHMS | 32 | 9 | 39 | 17 | 32 | 11 | 43 | 3 | 36,5 | 10 |
| TOTAL | 4617 | 1787 | 4487 | 2989 | 4195 | 2083 | 6750 | 976 | 5012,25 | 1958,75 |
In this table is highlighted the exact number of up – and down – regulated genes in each of 14 selected “macro – pathways”, for each time point is highlighted. The average value for each pathway, considering all time points, is also shown. UP. Up-regulated. DOWN. Down-regulated.