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. 2018 Dec 27;18(2):156–166. doi: 10.1080/15384101.2018.1560202

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Figure 6. — Effect of MIAT overexpression on neonatal rats of HI injury. Three days before conducting the neonatal rat model of HI injury, lentiviral vector lenti-NC or lenti-MIAT was injected into the cortex of neonatal rats. Then, neonatal rat model of HI injury was performed, and divided into lenti-NC (n = 6) and lenti-MIAT group (n = 6). (a) Twenty-eight days after the establishment of neonatal rat model of HI injury, motor function of rats was detected by grip-traction test. (b) Compared with lenti-NC group, lncRNA MIAT was upregulated in striatal tissues of lenti-MIAT group, whereas miR-211 was downregulated. (c) GDNF expression was up-regulated in striatal tissues of lenti-MIAT group than that of lenti-NC group. *p < 0.05, compared with leti-NC.