Table 1.
Comparison of pediatric GIST with adult GIST.
Characteristic | Pediatric GIST | Adult GIST |
---|---|---|
Incidence | Rare | Common |
Median age (years) | 13 | 50 |
Sex | Female predominance(70%) | Equal gender distribution |
Histology | Epithelioid and mixed | Spindle |
Gene profile | Wild Type KIT/PDGFR (85%) SDH mutation (85%) |
KIT mutation (85%) PDGFR mutation (5–10%) |
Primary site | Stomach (85%) | Stomach (50%) |
Lymph node metastasis | Common | Rare |