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. 2018 Sep 25;20(1):8–14. doi: 10.1080/15384047.2018.1504719

Table 1.

Comparison of pediatric GIST with adult GIST.

Characteristic Pediatric GIST Adult GIST
Incidence Rare Common
Median age (years) 13 50
Sex Female predominance(70%) Equal gender distribution
Histology Epithelioid and mixed Spindle
Gene profile Wild Type KIT/PDGFR (85%)
SDH mutation (85%)
KIT mutation (85%)
PDGFR mutation (5–10%)
Primary site Stomach (85%) Stomach (50%)
Lymph node metastasis Common Rare