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The expression of proteins related PI3K/AKT signaling pathway (a) Downregulation of PI3K/AKT signaling pathway contributed to RAI-resistance remission. Western blot presented the expression of PI3K, AKT and ERK, as well as their corresponding phosphorylated proteins. The data were from one representative experiment of three identically performed and were expressed as mean±SD. * P < 0.05, ** P < 0.01, *** P < 0.001.
