Table 3. Change on absolute and relative organ weights in NFD or HFD-fed mice.

Organs	Absolute organ weights (g), Relative organ weights (% of body weights)
Groups	Organ	Liver	Kidney	Pancreas	Periovarian fat pads	Abdominal wall fat pads
Controls
Intact	Absolute	1.051±0.057	0.214±0.013	0.248±0.018	0.110±0.015	0.044±0.025
	Relative	3.151±0.251	0.641±0.029	0.745±0.079	0.329±0.053	0.130±0.067
HFD	Absolute	1.750±0.063a	0.326±0.012a	0.241±0.013	0.853±0.104c	0.705±0.147c
	Relative	3.492±0.181a	0.650±0.041	0.481±0.025c	1.703±0.221c	1.402±0.267c
Reference
Metformin	Absolute	1.473±0.073ab	0.271±0.012ab	0.245±0.006	0.485±0.087cd	0.396±0.078cd
	Relative	3.369±0.141	0.620±0.034	0.560±0.017cd	1.106±0.173cd	0.906±0.182cd
Test material – BH
400 mg/kg	Absolute	1.346±0.050ab	0.248±0.013ab	0.245±0.013	0.241±0.047cd	0.229±0.040cd
	Relative	3.344±0.210	0.615±0.039	0.607±0.035cd	0.597±0.111cd	0.569±0.098cd
200 mg/kg	Absolute	1.472±0.086ab	0.269±0.007ab	0.242±0.006	0.491±0.078cd	0.386±0.060cd
	Relative	3.404±0.336b	0.621±0.040	0.560±0.041cd	1.138±0.226cd	0.892±0.148cd
100 mg/kg	Absolute	1.575±0.079ab	0.292±0.016ab	0.244±0.014	0.653±0.043cd	0.494±0.064cd
	Relative	3.456±0.277b	0.640±0.056	0.533±0.024cd	1.431±0.092cd	1.081±0.131cd

Values are expressed as Mean ± SD of 8 mice

NFD = Normal pellet diet; HFD = 45% kcal high fat diet

BH extract = Domestic blue honeysuckle (Berries of Lonicera caerulea L.) extracts

Metformin was administrated at a dose level of 250 mg/kg

^a p<0.01 as compared with the intact control group at time-matched point by LSD test

^b p<0.01 as compared with the HFD control group at time-matched point by LSD test

^c p<0.01 as compared with the intact control group at time-matched point by MW test

^d p<0.01 as compared with the HFD control group at time-matched point by MW test