Table 5. Changes in blood glucose levels and serum lipid contents in NFD or HFD-fed mice.
Items | Glucose (mg/dl) |
Total cholesterol (mg/dl) |
Triglyceride (mg/dl) |
Low density lipoprotein (mg/dl) |
High density lipoprotein (mg/dl) |
---|---|---|---|---|---|
Groups | |||||
Controls | |||||
Intact | 91.75±16.24 | 97.25±14.15 | 72.59014.96 | 17.63±3.81 | 89.25±18.87 |
HFD | 268.38±35.62e | 263.00±33.09e | 245.75±27.69a | 79.38±10.20a | 16.75±2.96a |
Reference | |||||
Metformin | 179.63±21.31ef | 178.13±19.66ef | 166.75±29.51ac | 53.88±12.09ac | 41.25±14.20ac |
Test material - BH | |||||
400 mg/kg | 128.25±10.78ef | 123.88±13.25ef | 117.75±20.32ac | 38.00±11.43ac | 70.63±17.42bc |
200 mg/kg | 177.25±26.69ef | 179.88±26.82ef | 164.00±21.11ac | 52.13±11.47ac | 41.38±12.37ac |
100 mg/kg | 210.38±37.28eg | 209.38±19.92ef | 194.88±12.57ac | 60.50±13.86ac | 30.38±10.20ad |
Values are expressed as Mean ± SD of 8 mice
NFD = Normal pellet diet; HFD = 45% kcal high fat diet
BH = Domestic blue honeysuckle (Berries of Lonicera caerulea L.) extracts
Metformin was administrated at a dose level of 250 mg/kg
a p<0.01 and b p<0.05 as compared with the intact control group at time-matched point by LSD test
c p<0.01 and d p<0.05 as compared with the HFD control group at time-matched point by LSD test
e p<0.01 as compared with the intact control group at time-matched point by MW test
f p<0.01 and g p<0.05 as compared with the HFD control group at time-matched point by MW test