Table 2.

Genes upregulated in SKOV3 tumors treated with anti-TGFBR2 IgG-8311.

Name	p value*	fold change*	TGF-β pathway*
CDH1	0.025	2.01	yes
SYNE1	0.021	1.62	yes
SLIT2	0.036	1.55	yes
SOX9	0.03	1.34	yes
JAG1	0.002	1.31	yes
SOX17	0.011	1.23
SMURF1	0.029	1.21	yes

*based on Nanostring analysis of tumor RNA for IgG-8311 treatment group relative to control IgG