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. 2018 Oct 19;11(1):129–144. doi: 10.1080/19420862.2018.1530920

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© 2018 The Author(s). Published by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 14. — Biological activities comparison of fractionated SB5 and the reference product.

TNF binding activity per fractions for charge variants of adalimumab (left) and CDC activity per fractions for charge variants of adalimumab (right). Results from 1 batch of SB5, 1 lot of EU Humira®, and 1 lot of US Humira® are presented.