Table 4.
Detected masses and relative levels of C-terminal peptide for CPB with/without samples.
| Sample | Lys Deleted C-terminus (SLSLSPG) |
Intact C-terminus (SLSLSPGK) |
|||
|---|---|---|---|---|---|
| Detected Mass (Da) | %Relative Areaa | Detected Mass (Da) | %Relative Areaa | ||
| SB5 | CPB (-) | 659.35 | 98.2 | 787.44 | 1.8 |
| CPB (+) | 659.35 | 100.0 | N/Db | N/Ac | |
| EU reference product | CPB (-) | 659.35 | 92.4 | 787.44 | 7.6 |
| CPB (+) | 659.35 | 100.0 | N/D | N/A | |
| US reference product | CPB (-) | 659.35 | 94.2 | 787.44 | 5.8 |
| CPB (+) | 659.35 | 100.0 | N/D | N/A | |
a The relative level of each peptide was determined by calculating the percentage area of integrated intensity for expected mass of each variant. b Not detected. Lower limit of detection. c Not applicable.