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. 2018 Oct 29;8(2):e1532763. doi: 10.1080/2162402X.2018.1532763

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© 2018 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 7. — Effects of ONCOS-102 and pembrolizumab on subsets of leukocytes in tumors on left and right flank. A. Percentage of hCD8+ leukocytes among hCD3+ leukocytes. B. percentage of hCD4+ leukocytes among hCD3+ leukocytes. C. Percentage of PD-L1+ leukocytes in tumors. The populations were gated with forward and side scattering (FSC-A/SSC-A dot plot) in leukocytic regions (at least 10⁴ cells/events were analyzed by flow cytometry, 6–8 tumors/experimental group have been analysed in one experimental replicate). Flow cytometry analysis was performed on FlowJo v10 software. Data represent mean ± SEM.