Figure 1.
MBL deficiency promotes tumor growth in a murine HCC model.
WT (n = 10) and MBL–/– mice (n = 10) received a tail vein intravenously injection of 2 × 106 Hepal-6 cells. After 3 weeks, mice were sacrificed and the visible liver tumor nodules, maximal tumor size (a) and liver index (b) were examined. Scale bars, 1 cm. (c) Analysis of Ki67 positive cells in tumor tissues by immunohistochemistry (each dot represents the average of 10 HPFs). Scale bars, 50 μm. Data are presented as means ± SEM (horizontal lines). HPFs, high-power fields; *, P < 0.05; **, P < 0.01.