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Fab13.7 lacks agonistic activity upon crosslinking.
Binding of a goat anti-human Fab antibody to Fab 13.7 in ELISA (a) and (b) the effect of this goat anti-human Fab antibody (64 µg/ml) on the stimulatory activity of Fab13.7 towards TNFR1 was analyzed in an IL-8 release assay using HT1080 cells and compared to ATROSAB (n = 2, mean ±SD).
