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. 2019 Jan 23;14(1):e0210314. doi: 10.1371/journal.pone.0210314

Table 4. Values and distribution of variables in the classification across the five proposed clusters.

Life area variables Cluster 1
(n = 13)
Cluster 2
(n = 43)
Cluster 3
(n = 108)
Cluster 4
(n = 47)
Cluster 5
(n = 13)
Statistical test, p
Bipolar disorder
Number of hospitalizations [Mean (SD)] 0.8 (0.6) 1.9 (2.6) 2.0 (2.5) 2.9 (2.4) 4.2 (3.1) 4.397,1 0.002
Number of suicide attempts [Mean (SD)] 0.4 (0.8) 0.7 (1.6) 0.6 (1.1) 0.9 (1.3) 2.1 (4.2) 3.008,1 0.019
Comorbid personality disorder, yes [n (%)] 0 (0.0) 1 (2.3) 17 (15.7) 14 (29.8) 9 (69.2) 37.421,2 <0.0005
Physical health
Body Mass Index [Mean (SD)] 24.2 (3.4) 24.9 (3.1) 27.7 (4.5) 32.3 (3.7) 36.2 (7.0) 30.902,1 <0.0005
Metabolic Syndrome, yes [n (%)] 1 (7.7) 5 (12.5) 28 (26.7) 19 (41.3) 5 (38.5) 12.445,1 0.014
Number of comorbid physical illnesses [Mean (SD)] 0.5 (0.5) 0.5 (0.7) 1.1 (1.3) 1.7 (1.9) 2.2 (2.0) 7.851,1 <0.0005
Cognition
SCIP category, no cognitive impairment [n (%)] 12 (92.3) 22 (51.2) 37 (35.6) 7 (14.9) 0 (0.0) 55.176,2 <0.0005
Real-world functioning
Permanently disabled due to bipolar disorder, yes [n (%)] 0 (0.0) 2 (4.7) 46 (42.6) 39 (83.0) 12 (92.3) 78.5372, <0.0005
FAST total score [Mean (SD)] 5.9 (6.1) 13.5 (7.8) 26.8 (14.3) 36.4 (13.4) 47.8 (10.2) 37.200,1 <0.0005
FAST leisure subscale score [Mean (SD)] 0.5 (0.8) 1.1 (1.2) 2.6 (1.8) 3.5 (1.9) 4.5 (1.7) 20.712,1 <0.0005
Health-related quality of life*
SF-36 physical functioning scale score [Mean (SD)] 0.4 (0.4) -0.1 (0.7) -0.3 (1.0) -0.8 (1.5) -1.2 (1.3) 7.216,1 <0.0005
SF-36 mental health scale score [Mean (SD)] 0.1 (0.7) 0.1 (1.0) -0.7 (1.1) -0.9 (1.3) -0.6 (1.2) 7.257,1 <0.0005

Abbreviations: FAST = Functioning Assessment Short Test; SCIP = Scale for Cognitive Impairment in Psychiatry; SD = standard deviation; SF-36 = The MOS 36-item Short-Form Health-Survey.

*. Standardized scores.

1. ANOVA test;

2. Chi-square test.