Table 4. Summary of comparison PACT-ADP and LTA.
ADP 5 uM | ADP 0.25 uM | |||||
---|---|---|---|---|---|---|
LTA normal (Median) |
LTA abnormal (Median) |
p-value | LTA normal (Median) |
LTA abnormal (Median) |
p-value | |
PAC1 | 97 | 95 | 0.23 | 81 | 77 | 0.39 |
CD62P | 84 | 75 | 0.0002 | 53 | 37 | 0.007 |
CD63 | 26 | 19 | 0.0007 | 9.8 | 6.4 | 0.015 |
Mann-Whitney U test: Expression of PAC1, CD62P (P-selectin) and CD63 (LAMP3) after activation with ADP (5 μM or 0.25 μM) expressed as % activated platelets are compared to the results of LTA.