Table 3. Clinical findings.
Characteristic | Colonized | Noncolonized | p Value |
---|---|---|---|
Number of patients (n, %) | 90 (40.9) | 130 (59.1) | |
Single induction chemotherapy (n, %) | 46 (51.1) | 61(46.9) | ns |
Double induction chemotherapy (n, %) | 44 (48.9) | 69 (53.1) | ns |
Allogenic stem cell transplantation as consolidation therapy (n, %) | 45 (50) | 61 (46.9) | ns |
Time to allogenic stem cell transplantation (median, range) | 134 (28–2349) | 111 (36–1865) | ns |
Length of hospital stay (median, range) | 50 (15–93) | 49 (8–84) | ns |
Days with fever (median, range) | 6 (0–28) | 5 (0–31) | 0.01 |
Patients requiring treatment on intensive care unit (n, %) | 23 (25.6) | 18 (13.9) | 0.035 |
Hemoglobin g/dl* (median, range) | 9.25 (4.3–16) | 8.85 (3.5–16.2) | ns |
Leukocytes/nl* (median, range) | 0.67 (0.12–12.5) | 0.62 (0.11–73.06) | ns |
Thrombozytes/nl* (median, range) | 28 (8–143) | 28 (7–185) | ns |
Day 15 bone marrow blast clearance (n, %) | 54 (60) | 86 (66.2) | ns |
Complete remission after induction chemotherapy (n, %) | 59 (65.6) | 96 (73.9) | ns |
C-reactive protein (median, range) | 4,92 (0.2–27.5) | 3,58 (0.4–34.3) | 0.005 |
Days with Grade 4 neutropenia (median, range) | 21 (1–86) | 21,5 (0–52) | ns |
Day 15 bone marrow blast clearance (n, %) | 54 (60) | 86 (66.2) | ns |
Complete remission after induction chemotherapy (n, %) | 59 (65.6) | 96 (73.9) | ns |
*Median of values recorded during hospital stay of induction chemotherapy. All p-values reported are two-sided. Statistical significance was defined as p≤0.05.