Fig 2. CPPs effect on cholesterol-pyrene multimers in function of temperature on PC LUVs.

The excimers/isoemisive ratio (474/432 nm) was followed at different temperatures during heating (A, continuous lines), or cooling (B, dotted lines) of the samples. CPPs were incubated with the LUVs at a 1/25 P/L ratio. Control CPP free LUVs (black ●,○), Penetratin (green ♦,◊), R9 (blue ▲,∆) and RW9 (red ■,□). Means ± SEM of 5 to 8 independent experiments. The stars in colour correspond to their respective experimental point colours compared to the control LUVs; * P<0.05, ** P<0.01, *** P<0.001 by unpaired t-test.