Table 5. Univariate multinomial logistic regression analysis to predict coronary plaque features.

	OR (95% CI)	p value	OR (95% CI)	p value	OR (95% CI)	p value
Predictors	CPV<50 vs HS		CPV>50 vs HS		CPV<50 vs CPV>50
LDLR promoter methylation	1.922 (0.892–4.139)	0.095	2.447 (1.135–5.274)	0.022	1.273 (0.958–1.693)	0.096
LDLR gene expression	0.660 (0.434–1.003)	0.051	0.660 (0.430–1.011)	0.056	1 (0.730–1.369)	0.998
SREBF2 gene expression	0.881 (0.699–1.109)	0.280	0.618 (0.447–0.855)	0.004	0.702 (0.513–0.961)	0.027
ABCA1 gene expression	0.851 (0.706–1.025)	0.089	0.735 (0.588–0.917)	0.007	0.863 (0.698–1.068)	0.175
Predictors	NCPV<50 vs HS		NCPV>50 vs HS		NCPV<50 vs NCPV>50
LDLR promoter methylation	1.940 (0.903–4.169)	0.089	2.440 (1.133–5.257)	0.023	1.258 (0.953–1.659)	0.105
LDLR gene expression	0.710 (0.467–1.080)	0.109	0.598 (0.383–0.932)	0.023	0.842 (0.598–1.185)	0.324
SREBF2 gene expression	0.910 (0.723–1.144)	0.418	0.522 (0.352–0.775)	0.001	0.574 (0.391–0.845)	0.005
ABCA1 gene expression	0.895 (0.746–1.073)	0.231	0.632 (0.485–0.823)	0.001	0.706 (0.549–0.908)	0.007
Predictors	TPV<100 vs HS		TPV>100 vs HS		TPV<100 vs TPV>100
LDLR promoter methylation	1.893 (0.876–4.093)	0.105	2.484 (1.149–5.372)	0.021	1.312 (0.976–1.764)	0.072
LDLR gene expression	0.675 (0.444–1.0124)	0.065	0.642 (0.418–0.987)	0.043	0.952 (0.695–1.306)	0.762
SREBF2 gene expression	0.896 (0.712–1.128)	0.351	0.580 (0.409–0.823)	0.002	0.648 (0.461–0.909)	0.012
ABCA1 gene expression	0.876 (0.729–1.053)	0.159	0.687 (0.541–0.872)	0.002	0.784 (0.624–0.984)	0.036

Bold values were considered statistically significant with a p < 0.05.ABCA1, ATP binding cassette subfamily A member; CHD, coronary heart disease; CI, confidence interval; CPV, calcified plaque volume; LDLR, Low density lipoprotein receptor; NCPV, non-calcified plaque volume; OR, odds ratio; SREBF2, sterol regulatory element-binding factor 2; TPV, total plaque volume.