Data from the hypo/hypercapnia experiment (Fig. 6) repeated in 3 animals with different drive field amplitudes (13 mT for rat 1, 11 mT for rat 2, and 14 mT for rat 3). Four raw data cycles are overlaid as well as the mean data for each animal. The Fe concentration in the blood varies for each animal based on the timing of the experiment post-infusion (~70 min for rat 1, ~70 min for rat 2, ~160 min for rat 3). The absolute signal level and noise varies for the different experiments based on the drive field amplitude, SPIO concentration in the blood, detector positioning, and ∆paCO2. However, a percent signal change of 8–10% was observed in all experiments.