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. Author manuscript; available in PMC: 2019 Jan 23.
Published in final edited form as: Mod Pathol. 2010 Mar 26;23(7):991–999. doi: 10.1038/modpathol.2010.72

Figure 3.

Figure 3

G-banded karyogram and interphase FISH from two patients with a plasmablastic lymphoma. The pleural effusion karyotype (case 2) was complex. A translocation between chromosomes 8 and 22, (t(8;22)(q24.1;q11.2)) (arrows), and rearrangements of chromosome 1, loss of chromosome 13, and gain of chromosomes 3 and 5 were detected (a). Interphase FISH revealed one fusion (intact MYC), one red (5ʹ MYC), and one green (3ʹ MYC) signals confirming the rearrangement of MYC (b). The small intestine and testis (case 1) showed gain of one copy of 5p (green signal), as well as gains of chromosomes 9 (aqua signal) and 15 (red signal) centromeres.