Table 6:

Adjusted average effect estimates (β) associated with symptom duration subgroup (>60 months) for postoperative improvements in PROMs and clinical measures of disease severity

PROM scores:	Adjusted β	SE	95% CI	p-value	R2
SNOT-22 total score1	−14.3	4.2	−22.6, −5.9	0.001	0.366
Rhinologic domain2	−3.8	1.7	−7.1, −0.5	0.023	0.122
Ear / facial domain3	−2.9	1.1	−5.1, −0.8	0.009	0.091
Psychological dysfunction4	−5.1	1.7	−8.5, −1.7	0.004	0.412
RSDI total score5	−10.9	5.1	−21.0, −0.7	0.036	0.269
Physical domain6	−4.5	1.9	−8.3, −0.7	0.020	0.137
BSIT score7	1.9	0.9	−0.2, 3.5	0.072	0.184

PROMs, patient reported outcome measures; β, effect estimate for the predictor of interest; SE, standard error, CI, confidence interval; R², coefficient of multiple determination (explained percent variance); SNOT-22, 22-item SinoNasal Outcome Test; RSDI, Rhinosinusitis Disability Index; BSIT, Brief Smell Identification Test.

¹Final model adjusted for covariates including: enrollment site (p=0.236), employer provided insurance (p=0.001), and $0-$25,000 income level (p=0.005).

²Final model adjusted for covariates including: enrollment site (p=0.390), employer provided insurance (p=0.045).

³Final model adjusted for covariates including: enrollment site (p=0.964).

⁴Final model adjusted for covariates including: enrollment site (p=0.021), employer provided insurance (p=0.002), $0-$25,000 income level (p<0.001), and preoperative CT score (p=0.033).

⁵Final model adjusted for covariates including: enrollment site (p=0.633), $0-$25,000 income level (p=0.017), and Medicare insurance (p=0.008).

⁶Final model adjusted for covariates including: enrollment site (p=0.972) and White/Caucasian race (p=0.042).

⁷Final model adjusted for covariates including: enrollment site (p=0.186) and nasal polyposis (p=0.046).