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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Pain. 2019 Feb;160(2):334–344. doi: 10.1097/j.pain.0000000000001414

Figure 6. Both optogenetic and chemogenetic manipulation do not affect locomotor function of mice.

Figure 6

(A and B) Optogenetic manipulation (both NpHR-mediated neuronal inhibition and ChR2-mediated neuronal excitation) of Sp5C D1-expressing neurons in D1-Cre mice had no significant effects on falling speed (A) and time to fall (B) in the Rotarod testing. (C and D) Chemogenetic activation of Sp5C D1-expressing neurons in D1-Cre mice had no significant effects on falling speed (C) and time to fall (D) in the Rotarod testing. n = 6 mice per group.