Table III.
Fusion Summarya
Sera Reactivity (IgG/IgA) |
|||||||
---|---|---|---|---|---|---|---|
Mouse | Virus | gp120 or gp120- CD4 FLSCb |
gp41 | Fusion | Weeks Infectedc |
Splenocyte number |
Percent Positived |
C5M3 | BaL | +/+ | −/− | F860 | 8 | 12X106 | 5% |
C5M2 | BaL | +/− | +/− | F861 | 8 | 30X106 | 7% |
Ms#1 | BaL | +/+ | +/+ | F862 | 4 | 54X106 | 22% |
13.41 M1 | JrFl | +/NTe | +/NT | F878 | 34 | 3.3X106 | 18% |
A total of four separate fusions were performed under same conditions
Sera was collected from animals prior to sacrifice and tested for IgG or IgA immunoreactivity with gp120, gp120-CD4 FLSC or gp41
The length of time mice were infected prior to euthanasia/fusion is indicated in weeks
Percent positive is the number of HIV-1 specific antibodies isolated
NT= not tested