. Author manuscript; available in PMC: 2020 Mar 1.

Published in final edited form as: Pediatr Blood Cancer. 2018 Nov 4;66(3):e27538. doi: 10.1002/pbc.27538

TABLE 3.

Discriminant Validity: area under the curve (AUC) for screening tool total scores and psychosocial subscale scores against reference standard cases

Reference standards	Case definition	Total scores, AUC (95% CI)	Psychosocial subscale scores, AUC (95% CI)
High pain frequency	Pain frequency ≥ 15 days/month	.82 (.71 - .93)^***	.81 (.68 - .93)^***
	SCD Pain Burden Days ≥ many	.83 (.74 - .92)^***	.82 (.71 - .93)^***
Persistent pain duration	Duration ≥ 6 months	.63 (.50 - .77)	.65 (.52 - .78)^*
Moderate to severe disability	FDI ≥ 13	.93 (.87 - .98)^***	.86 (.78 - .95)^***
High pain interference	Pain Interference T-score ≥ 65	.80 (.68 - .93)^***	.80 (.66 - .94)^***
High inpatient admissions	Admissions for pain ≥ 3	.74 (.62 - .86)^**	.77 (.66 - .89)^***
High ED visits	ED visits for pain ≥ 3	.69 (.55 - .82)^*	.67 (.53 - .82)^*
Elevated depressive symptoms	CDI T-score ≥ 65	.76 (.63 - .88)^***	.69 (.53 - .85)^*
High pain catastrophizing	PCS-C ≥ 26	.75 (.64 - .86)^***	.72 (.60 - .84)^***
High pain-related fear	FOPQ ≥ 51	.83 (.73 - .92)^***	.80 (.70 - .90)^***
Psychosocial distress index (CDI, PCS, FOPQ)	Case on two or more psychosocial variables^┼	.78 (.67 - .89)^***	.76 (.64 - .88)^***

Note: FDI = Functional Disability Inventory; ED = emergency department; CDI = Children’s Depression Inventory-2; PCS-C = Pain Catastrophizing Scale for Children; FOPQ = Fear of Pain Questionnaire.

^┼

Psychosocial variables include depressive symptoms, catastrophizing, and fear of pain

p < .05,

^**

p < .01,

^***

p < .001