Skip to main content
. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Arch Toxicol. 2018 Oct 15;93(1):163–178. doi: 10.1007/s00204-018-2331-8

Figure 3: MT treatment resulted in caspase-3 activation and pro-caspase cleavage in the liver.

Figure 3:

Mice were treated with 300 mg/kg APAP, and 20 mg/kg MT or saline was given 1.5 h later. A group of mice was treated with Gal/ET for 6h as the positive control of apoptosis. (A) Caspase-3 activity in liver homogenate. (B) Pro-caspase-3 cleavage analyzed with western blotting. Bars represent means ± SEM for n = 4 mice per group. *p<0.05 vs. Ctrl. #p<0.05 vs. APAP.