Figure 4.

Cells Shift from a Naive-like to a Primed-like Expression Pattern during Early Embryonic Development

Naive and primed markers were identified from the DE analysis of the hESC data. New cells are mapped onto the naive-primed axis based on the proportions of naive and primed markers that they express. This was performed for cells derived from mouse embryos (A), cynomolgus monkey embryos (B), and human pre-implantation embryos (C). For each plot, the density of cells is represented by the color of the pixels. Cells on the red line have equal proportions of expressed primed and naive markers.

See also Figure S4.