Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 20;24(2):162–166. doi: 10.1038/s41380-018-0225-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — Dissemination of mHtt via the bloodstream. (a) WT and zQ175 adult mice underwent parabiosis. Blood sampling was performed every 3 weeks where the various cellular elements were isolated. (b) mHtt was detected in white blood cells from WT mice 3, 6, 9 and 12 months post surgery, as well as in platelets and red blood cells (data not shown). (c) Post-mortem analyses indicate the presence of mHtt (antibody S829 provided by Gillian Bates; DAB) in several peripheral organs including kidney and muscle tissue in WT mice, 9 months post surgery. Scale bars: 10 µm