Table 1.
Demographic, clinical and neuropsychological data by diagnosis.
| HC | sMCI | cMCI | AD | ||
|---|---|---|---|---|---|
| (n 113) | (n 101) | (n 20) | (n 119) | p | |
| Gender (n,M/F) | 52/61 | 53/48 | 12/8 | 48/71 | 0.094 |
| Age (years) | 73.0 ± 6.5 | 74.7 ± 5.4 | 72.2+6.5 | 75.6 ± 6.0a | 0.005 |
| Years of education | 10.7 ± 4.7 | 8.7 ± 4.2 | 9.7+4.4 | 7.9 ± 3.9b | <0.0001 |
| MMSE score | 29.0 ± 1.2 | 27.1 ± 1.6 | 26.9+1.9 | 20.7 ± 4.6b | <0.0001 |
| APOE4 genotype (+ive, -ive) | 32/74 | 25/62 | 12/5 | 58/44b | <0.0001 |
HC, Healthy controls; sMCI, stable MCI; cMCI, converter MCI; AD, Alzheimer’s disease; +ive, positive; -ive, negative where available. Data are shown as mean ± standard deviation. Chi-square was used for gender and APOE4 genotype comparisons. ANOVA was used for age, education, and MMSE. Bonferroni pairwise comparisons: aAD vs. HC p = 0.010; bAD vs. HC p < 0.0001.