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. 2019 Jan 17;9:3351. doi: 10.3389/fmicb.2018.03351

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Copyright © 2019 Liang, Sproule, Haltli, Marchbank, Berrué, Overy, McQuillan, Lanteigne, Duncan, Correa and Kerr.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Microbial biotransformations of HHQ/PQS. (A) Oxidation of HHQ by P. aeruginosa (PqsH) (Gallagher et al., 2002), Rhodococcus sp. BG43 and Streptomyces sp. RKBH-B178. (B) Glucuronidation of PQS by Streptomyces sp. RKBH-B178. (C) Degradation of PQS to anthranilic acid (7) by Rhodococcus sp. BG43 (Muller et al., 2014). (D) Degradation of PQS to N-octanoylanthranilic acid (8) by Arthrobacter nitroguajacolicus strain Rü61a (Hod) (Pustelny et al., 2009). (E) Oxidation of PQS to HHQD (9) by Achromobacter xylosoxidans Q19 (Soh et al., 2015).