Table 1.
List of genes differentially expressed between cervical cancer derived cell lines and PHK.
Gene | Description | C33A | SiHa | HeLa | |||
---|---|---|---|---|---|---|---|
Fold (*) | p-value | Fold | p-value | Fold | p-value | ||
BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 4,20 | 0,00016 | 2,39 | 0,00395 | 2,07 | 0,01392 |
DMC1 | DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) | −6,21 | 0,03704 | 9,06 | 0,00607 | −3,02 | 0,00553 |
EXO1 | Exonuclease 1 | 6,11 | 0,00180 | 5,14 | 0,00001 | 3,02 | 0,00587 |
FANCG | Fanconi anemia, complementation group G | 4,35 | 0,00098 | 4,08 | 0,02178 | 3,70 | 0,04354 |
FEN1 | Flap structure-specific endonuclease 1 | 4,71 | 0,00912 | 4,44 | 0,0247 | 4,25 | 0,01481 |
GTSE1 | G-2 and S-phase expressed 1 | 9,31 | 0,00035 | 4,87 | 0,0002 | 3,94 | 0,00044 |
IGHMBP2 | Immunoglobulin mu binding protein 2 | 4,74 | 0,0029 | 9,39 | 0,01658 | 3,26 | 0,00429 |
LIG1 | Ligase I, DNA, ATP-dependent | 13,04 | 0,00053 | 15,29 | 0,01269 | 9,78 | 0,00048 |
MAP2K6 | Mitogen-activated protein kinase kinase 6 | 10,81 | 0,04978 | 29,68 | 0,00472 | 36,53 | 0,01302 |
MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 3,59 | 0,00906 | 4,76 | 0,01521 | 4,17 | 0,00804 |
MSH4 | MutS homolog 4 (E. coli) | 17,53 | 0,0018 | −2,99 | 0,01202 | −4,55 | 0,03382 |
NTHL1 | Nth endonuclease III-like 1 (E. coli) | 5,13 | 0,00044 | 3,63 | 0,01203 | 3,40 | 0,0154 |
RAD51 | RAD51 homolog B (S. cerevisiae) | 2,83 | 0,01412 | 6,66 | 0,0025 | 3,65 | 0,01687 |
RAD54L | RAD54-like (S. cerevisiae) | 2,28 | 0,00371 | 3,43 | 0,02211 | 2,61 | 0,00442 |
RAD9A | RAD9 homolog A (S. pombe) | 6,15 | 0,00222 | 12,28 | 0,01104 | 4,66 | 0,00397 |
RPA1 | Replication protein A1, 70 kDa | 2,78 | 0,00021 | 5,06 | 0,00641 | 2,41 | 0,00443 |
SMC1A | Structural maintenance of chromosomes 1A | 8,03 | 0,00034 | 15,54 | 0,00249 | 4,68 | 0,03638 |
TREX1 | Three prime repair exonuclease 1 | −2,48 | 0,00054 | 4,56 | 0,00846 | 2,96 | 0,00055 |
*Only genes with fold >2 or fold <−2 were included.