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. 2019 Jan 23;9:326. doi: 10.1038/s41598-018-36841-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Inhibition of binding of the endogenous LARP6 in cell extracts. (A) Gel mobility shift experiment with extracts of human lung fibroblasts (HLFs) treated with the indicated concentrations of C9 and using radiolabeled 5′SL RNA as probe. The migration of free RNA and 5′SL RNA/LARP6 complex is indicated. (B) Altered electrophoretic mobility of endogenous LARP6 after C9 treatment of cells. Western blot of LARP6 in the extracts from A. Migration of LARP6 is indicated.