Table 2.

Definition of Clinical Deterioration within 72 Hours.

Fulfillment of Any of the following criteria:

Transfer to an ICU (if originally located in a non-ICU)

Initiation of High Flow Nasal Cannula, Non-Invasive Positive Pressure Ventilation or Invasive Positive Pressure Ventilation

Receipt of ≥60 mL/kg of crystalloid if <50 kg OR ≥3 L of crystalloid if ≥50 kg

Initiation of Inotropic of Vasopressor Support (epinephrine, norepinephrine, vasopressin, phenylephrine, milrinone, dopamine)

New Onset Altered Mental Status (significant decline in GCS, somnolence, seizure)

Death