Table S1. PEDro study quality score and Cochrane risk of bias assessment.
| Authors | Year | PEDro score | Selection bias: randomization | Selection bias: concealment | Performance bias | Detection bias | Attrition bias | Reporting bias |
|---|---|---|---|---|---|---|---|---|
| Chen et al. | 2012 | 7 | Low risk | High risk | High risk | Low risk (OS only) | Low risk | Low risk |
| Govindan et al. | 2011 | 6 | Low risk | Low risk | High risk | Low risk | Low risk | Low risk |
| Gregorc et al. | 2013 | 7 | High risk | High risk | High risk | High risk | Low risk | Low risk |
| Groen et al. | 2011 | 7 | Low risk | High risk | Low risk | High risk | Low risk | Low risk |
| Heymach et al. | 2008 | 8 | Low risk | High risk | High risk | High risk | Low risk | Low risk |
| Hoang et al. | 2013 | 6 | Low risk | High risk | Unclear risk | High risk | Low risk | Low risk |
| Jelic et al. | 2001 | 7 | Low risk | High risk | High risk | High risk | Low risk | Low risk |
| Johnson et al. | 2004 | 9 | Low risk | Low risk | High risk | High risk | Low risk | Low risk |
| Kubota et al. | 2008 | 7 | Low risk | Low risk | High risk | Low risk (OS only) | Low risk | Low risk |
| Langer et al. | 2014 | 8 | Low risk | Low risk | High risk | High risk | Low risk | Low risk |
| Lara et al. | 2011 | 8 | Low risk | Low risk | Low risk | Low risk | Low risk | Low risk |
| Lee et al. | 2009 | 11 | Low risk | Low risk | Low risk | High risk | Low risk | Low risk |
| Lilenbaum et al. | 2008 | 7 | Low risk | Low risk | High risk | Low risk (OS only) | Low risk | Low risk |
| Lynch et al. | 2012 | 9 | Low risk | Low risk | Low risk | High risk | Low risk | Low risk |
| Lynch et al. | 2010 | 8 | Unclear risk | Low risk | High risk | High risk | Low risk | Low risk |
| Morabito et al. | 2013 | 8 | Low risk | Low risk | High risk | Low risk (OS only) | High risk | Low risk |
| Novello et al. | 2014 | 11 | Low risk | Unclear risk | High risk | High risk | Low risk | Low risk |
| Paz-Ares et al. | 2013 | 11 | Low risk | Low risk | Low risk | Low risk | Low risk | Low risk |
| Pirker et al. | 2009 | 8 | Low risk | Low risk | Low risk | Low risk (OS only) | Low risk | Low risk |
| Reck et al. | 2013 | 11 | Low risk | Low risk | High risk | Low risk | Low risk | Low risk |
| Sandler et al. | 2010 | 7 | Low risk | Low risk | High risk | Low risk | Low risk | Low risk |
| Scagliotti et al. | 2008 | 7 | Low risk | Low risk | High risk | Low risk (OS only) | Low risk | Low risk |
| Scagliotti et al. | 2010 | 11 | Low risk | High risk | High risk | Low risk | Low risk | Low risk |
| Schuette et al. | 2009 | 8 | High risk | High risk | High risk | Low risk | Low risk | Low risk |
| Sculier et al. | 2004 | 9 | Low risk | Low risk | High risk | Low risk | Low risk | Low risk |
| Socinski et al. | 2012 | 8 | Low risk | High risk | High risk | Low risk | Unclear risk | Low risk |
| Spigel et al. | 2013 | 6 | Low risk | High risk | High risk | Low risk | Low risk | Low risk |
| Spigel et al. | 2015 | 7 | Low risk | Low risk | High risk | Low risk | Low risk | Low risk |
| Tan et al. | 2009 | 9 | Low risk | Low risk | High risk | High risk | Low risk | Low risk |
| Thatcher et al. | 2014 | 8 | Low risk | Low risk | High risk | Low risk | Low risk | Low risk |
| Treat et al. | 2010 | 7 | Low risk | Low risk | Unclear risk | Low risk | High risk | Low risk |
| Von Pawel et al. | 2013 | 9 | Low risk | Low risk | High risk | High risk | High risk | Low risk |
| Yoshioka et al. | 2013 | 8 | Low risk | Low risk | High risk | Low risk (OS only) | Low risk | Low risk |
| Zhang et al. | 2013 | 8 | Low risk | Low risk | High risk | Low risk | Low risk | Low risk |
| Zwitter et al. | 2009 | 8 | Low risk | High risk | High risk | Low risk | Low risk | Low risk |
OS, overall survival.