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. 2018 Nov 8;47(2):634–647. doi: 10.1093/nar/gky1088

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — TbMCM-BP is required for transcription regulation. Transcription was examined by stranded RNA-seq. Forward and reverse reads were analyzed separately. Chromosomes were analyzed with sliding window (5 kb bin, 1 kb step). Log₁₀(RPM) was plotted over the chromosome length. Chromosome 7 is shown as an example. The graph on the top represents forward read map: grey area is day 0 and blue line is day 2 after TbMCM-BP depletion. The graph on the bottom represents reverse read map: grey area is day 0 and red line is day 2 after TbMCM-BP deletion. The bar diagram in the middle depicts PTUs. Blue genes are transcribed in reverse PTUs and red are forward PTUs.