Table 1.

Quantification of nuclear ITCH levels in indicated BC subtypes and pathohistological grades in TNBC (italicized)

Breast cancer subtype	Negative	Low	Medium	High	Total	P valuea
Luminal A/B	73	17	28	3	121	<0.05
Her2+	19	6	0	0	25
Triple-negative (TNBC)	16	24	32	64	136
Stage I	6	4	10	13	33	<0.01
Stage II	7	6	5	23	41
Stage III	0	1	5	7	13
Stage IV	0	0	0	2	2
Unknown	3	13	12	19	47
Total	108	47	60	67	282

^a P values indicate the relationship between the levels of nuclear ITCH expression and different BC subtypes (top) or clinicopathological grades in TNBC (bottom).