Table 4.
SCR curation in human
| Protein isoform | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Stop codonsa | Canonical | Readthrough | ||||||||
| Gene | Gene ID | uStop | dStop | SCR signal | Accession | Lengthb | Accession | Lengthb | C-terminal extensionb | Expt evidencec |
| ACP2 | 53 | UGA | UAG | 2° structure | NP_001601.1 | 423 | NP_001343945.1 | 434 | 11 | 23 |
| AGO1 | 26523 | UGA | UAG | ND | NP_036331.1 | 857 | NP_001304051.1 | 891 | 34 | 15 |
| AQP4 | 361 | UGA | UAA | UGACUAG | NP_001641.1 | 323 | NP_001304313.1 | 352 | 29 | 16 |
| LDHB | 3945 | UGA | UAG | UGACUAG | NP_002291.1 | 334 | NP_001302466.1 | 341 | 7 | 18, 19 |
| MAPK10 | 5602 | UGA | UGA | UGACUAG | NP_620448.1 | 464 | NP_001304998.1 | 478 | 14 | 16 |
| MDH1 | 4190 | UGA | UGA | UGACUAG | NP_005908.1 | 334 | NP_001303303.1 | 353 | 19 | 19 |
| MPZ | 4359 | UAG | UGA | AAAUAGCGG | NP_000521.2 | 248 | NP_001302420.1 | 312 | 64 | 12 |
| MTCH2 | 23788 | UGA | UAG | ND | NP_055157.1 | 303 | NP_001304160.1 | 314 | 11 | 15 |
| OPRK1 | 4986 | UGA | UGA | UGACUAG | NP_000903.2 | 380 | NP_001305426.1 | 409 | 29 | 16 |
| OPRL1 | 4987 | UGA | UAG | UGACUAG | NP_872588.1 | 370 | NP_001305782.1 | 399 | 29 | 16 |
| SACM1L | 22908 | UGA | UGA | 2° structure | NP_054735.3 | 587 | NP_001306000.1 | 609 | 22 | 23 |
| VEGFA | 7422 | UGA | UGA | Ax element | NP_001165097.1 | 191 | NP_001303939.1 | 213 | 22 | 15 |
| VDR | 7421 | UGA | UGA | UGACUAG | NP_000367.1 | 427 | NP_001351014.1 | 494 | 67 | 17 |
aUpstream (uStop) and downstream (dStop) stop codons, ND, not determined.
bThe numerical values indicate number of aa residues.
cReference for experimental evidence of readthrough.