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. 2017 May 11;25(1):140–159. doi: 10.1177/1933719117704905

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Figure 5. — A, Transforming growth factor β1 (TGFβ1)/ZEB1/miR-200b feedback loop for endometriotic epithelial cells in EMT. B, miR-200b/ZEB1 double-negative feedback loop for endometriotic stromal cells in MET. C, miR-1827/miR-504 model of target genes and pathways in endometriotic epithelial cells. BMP2 indicates Bone Morphogenetic Protein 2; COX2 (PTGS2), Prostaglandin-endoperoxide Synthase 2; DNTTIP1, deoxynucleotidyltransferase terminal interacting protein 1; ELMSAN1, (MIDEAS) ELM2 and Myb/SANT domain containing 1; EMT, epithelial–mesenchymal transition; FGF2, Fibroblast Growth Factor 2; FOXO, Forkhead Box; HDAC1, histone deacetylase 1; IL-1B, Interleukin 1B; KLF2/4, Kruppel Like Factor 2/4; MET, mesenchymal–epithelial transition; MMP2, Matrix Metallopeptidase 2; NQO1, NAD(P)H Quinone dehydrogenase 1; NRP2, neuropilin 2; OCT4 (POU5F1), POU class 5 homeobox 1; PLXNA4, plexin A4; SEMA, semaphorin; SOX2, SRY-box 2; MMP2, Matrix Metallopeptidase 2; TGFβ1, transforming growth factor beta 1; VEGF, Vascular Endothelial Growth Factor; ZEB1, Zinc finger E-box Binding protein 2.