Table 1.
Characteristics | Clinical Pregnancy | Conception | ||||
---|---|---|---|---|---|---|
Positive (n = 180) | Negative (n = 885) | P-value | Positive (n = 218) | Negative (n = 847) | P value | |
Age | 36.1 (±3.8) | 37.1 (±3.8) | 0.002 | 36.3 (±3.8) | 37.1 (±3.8) | 0.007 |
BMI | 0.70 | |||||
Underweight (< 18.5) Normal (18.5–24.9) Overweight (25.0–29.9) Obese (> 30) |
4 (2.2%) 78 (43.3%) 38 (21.1%) 38 (21.1%) |
13 (1.5%) 469 (53.0%) 185 (20.9%) 159 (18.0%) |
0.69 | 6 (2.7%) 90 (41.3%) 52 (23.8%) 47(21.9%) |
11 (1.3%) 457 (54.0%) 171 (20.2%) 150 (17.7%) |
|
Infertility Diagnosis | < 0.001 | |||||
Male Factor Ovulatory Dysfunction Unexplained Other |
40 (22.2%) 50 (27.8%) 36 (20.0%) 62 (34.4%) |
193 (21.8%) 161 (18.2%) 199 (22.5%) 371 (41.9%) |
< 0.001 | 45 (20.6%) 62 (28.4%) 47 (21.6%) 73 (33.5%) |
188 (22.2%) 149 (17.6%) 189 (22.3%) 354 (41.8%) |
|
Anti-Mullerian Hormone (pmol/L) | 14.8 (±17.6) | 14.5 (±18.9) | 0.87 | 16.0 (21.7) | 14.2 (± 17.9) | 0.31 |
Antral Follicle Count | 14.5 (±9.7) | 13.0 (±9.1) | 0.08 | 14.3 (±9.74) | 13.0 (±9.10) | 0.10 |
Total Motile Sperm Count (millions) | 18.7 (±11.9) | 17.1 (±12.4) | 0.099 | 19.2 (±13.2) | 16.9 (±12.0) | 0.02 |
Total FSH Dose | 993.5 (±675) | 1123.9 (±858) | 0.059 | 1002.1 (± 653) | 1127.7 (± 870) | 0.050 |
Number of Dominant Follicles (≥ 15 mm) | 2.5 (±1.3) | 2.1 (±1.2) | 0.002 | 2.44 (±1.29) | 2.11 (±1.20) | 0.001 |
Peak Estrogen Level (pmol/L) | 2967 (±1507) | 2706 (±1493) | 0.035 | 2928 (±1458) | 2701 (±1506) | 0.05 |
Peak EST (mm) | 9.54 (±1.78) | 9.36 (±1.89) | 0.235 | 9.55 (±1.83) | 9.35 (±1.88) | 0.159 |
Differences in factors previously identified as significantly impacting pregnancy outcome between clinically pregnant and negative cycles. All continuous variables are expressed as mean ± SD